Brian Rafferty

Picture of Brian Rafferty

Assistant Professor
Deputy Chairperson


Office: N-684

Office Hours:

Phone: +1 (212) 220-8000;ext=1252



Bachelors of Science in Biology
SUNY Binghamton 2003

Doctorate of Philosophy (PhD) in Cell and Molecular Biology
SUNY Binghamton 2008

Courses Taught

BIO 109 (General Biology)
BIO 210 (Biology I)
BIO 220 (Biology II)

Research and Projects

  • The overarching theme of my research is to examine the role of natural extracts on regulation of inflammatory processes in various human cell lines through the use of various cell and molecule methodologies.
    • One aspect of my research looks at how these extracts influence the pro-inflammatory signals, specifically IL-1, known to be present in chronic inflammatory conditions such as Crohn’s disease and Ulcerative Colitis.
    • Another avenue we investigate is the role extracts play in the interaction between the pathogenic oral bacteria, Porphyromonas gingivalis, and various types of cells found in the oral cavity.


R. Piszczatowski, B. Rafferty, A. Rozado, J. Parziale and N. Lents. Myeloid zinc finger 1 (MZF-1) regulated expression of the CCN2/CTGF and CCN3/NOV genes in the hematopoietic compartment. 2015. J Cell Physio. 230:2634-2639.

R. Piszczatowski, B. Rafferty, A. Rozado, S. Tobak and N. Lents. The glyceraldehyde 3-phosphate dehydrogenase gene (GAPDH) is regulated by myeloid zinc finger 1 (MZF-1) and is induced by calcitriol. 2014. Biochem Biophys Res Commun. 451:137-141.

B. Rafferty, B. Unger, A. Perey, S. Tammariello, S. Pavlides and D. McGee. A novel role for the Rho Associated Kinase, ROCK, in IL-1 stimulated intestinal epithelial cell responses. 2013. Cell Immunol. 280:148-155.

A. Pollreisz, B. Rafferty, E. Kozarov and E. Lalla. Klebsiella pneumoniaeinduces an inflammatory response in human retinal-pigmented epithelial cell. 2012. Biochem Biophys Res Commun. 418: 33-37.

B. Rafferty, D. Jönsson, S. Kalachikov, R. Demmer, R. Nowygrod, H. Bush, Jr., M.S.V. Elkind and E. Kozarov. Impact of monocytic cells on recovery of uncultivable bacteria from atherosclerotic lesions. 2011. J Intern Med. 270: 273-280.

S. Dolgilevich, B. Rafferty, D. Luchinskaya and E. Kozarov. Genomic comparison of invasive and rare non-invasive strains reveals P. gingivalisgenetic polymorphisms. 2011. J. Oral Microbiology. 3:5764.

B. Rafferty, S. Dolgilevich, S. Kalachikov, I. Morozova, J. Ju, Susan Whittier, R. Nowygrod, and E. Kozarov. Cultivation of Enterobacter hormaecheifrom human atherosclerotic tissue. 2011. J Atheroscler Thromb. 18:72-81.

B. Rafferty, G. Li, and D.W. McGee. Activation of the α3 integrin affects TRAF6 function in the IL-1 signaling pathway of Caco-2 epithelial cells. 2010. Immunol Invest. 39:1-10.

Honors, Awards and Affiliations

Additional Information